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小脳失調の責任病巣は多数ある。橋底部にある橋核神経細胞、その遠心路である橋小脳線維、中小脳脚、小脳白質、オリーブ小脳線維、小脳のプルキンエ細胞のなどが変性、脱落する。

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歩行時のふらつきなどが現れるオリーブ橋小脳萎縮症とは? 多系統萎縮症の病型を解説

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多系統萎縮症は、脳や脊髄の神経細胞の変性によってさまざまな症状が現れる病気です。明確な原因はまだ解明されていませんが、患者の脳内には特定のタンパク質が異常に蓄積することがわかっています。

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小脳症状には甲状腺刺激ホルモン放出ホルモンの内服(タルチレリン)および点滴(プロチレリン)を行います。

発症以前から行っていた仕事や活動に制限はあるが、日常生活は自立している状態である

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